This page shows a number of applications of IMP to biological systems. They can be adapted to tackle other similar problems, or to add new input data to an existing system.
Each system links to its web page, where all the input files can be found, complete with running instructions. Most systems are permanently archived (via DOIs) at Zenodo; newer systems are also deposited at PDB-Dev.
Every system is periodically tested with the latest version of IMP to make sure it works. The most recent version of IMP that it works with is shown below (or see all builds).
See the IMP manual for information on adding a new system to this page.
All systems with the PMI1 tag are shown. [Show all systems]
Modeling the structures of complexes between the 26S proteasome and proteasome interacting proteins [more...]
Determination of the molecular architecture of the 40S•eIF1•eIF3 translation initiation complex [more...]
Human complement modeling [more...]
Modeling exosome complexes from cross-link MS data [more...]
Example of using IMP and PMI to model integrin [more...]
Modeling of the yeast Mediator complex [more...]
Modeling of the yeast Nuclear Pore Complex [more...]
Modeling of the Nup82 subcomplex of the Nuclear Pore Complex [more...]
Modeling of the Nup84 subcomplex of the Nuclear Pore Complex [more...]
Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex [more...]
Modeling of the SEA complex [more...]
Modeling of the TFIIH complex using chemical cross-links and electron microscopy (EM) density maps [more...]