IMP logo

News

Jun 13, 2024
The IMP 2.21.0 release is a minor update and bugfix release, adding support for spatiotemporal modeling and nested sampling-based optimization of representation. This is also the last version of IMP to support Python 2; please port your workflows to Python 3.
Apr 4, 2024
The IMP 2.20.2 release is a minor bugfix release, correcting build issues with Boost 1.84 and latest SWIG, and adding support for ARM64 .deb packages.
Jan 16, 2024
The IMP 2.20.1 release is a minor bugfix release, introducing compatibility with Python 3.12 and SWIG 4.2, and fixing a crash in the soap_score tool when scoring multiple models with an orientation-dependent SOAP score.
Dec 21, 2023
The IMP 2.20.0 release contains minor updates, including improved support for mmCIF files, reduced memory utilization, and preliminary support for converting RMF format directly to mmCIF.
Jun 22, 2023
The IMP 2.19.0 release contains minor updates, including serialization support for many commonly-used IMP classes, and support for capturing information on most IMP restraints in output RMF files.
Dec 15, 2022
The IMP 2.18.0 release contains minor updates, including preliminary support for serialization, improvements in constructing topology from primary sequence, and support for the PrISM method for annotation of ensemble precision.
Jun 23, 2022
The IMP 2.17.0 release contains minor updates, with a number of performance improvements and support for newer C++ standards.
Dec 16, 2021
The IMP 2.16.0 release contains major updates, most notably improved NumPy integration, support for Python 3.10, and a faster scoring function for Monte Carlo sampling.
Jun 02, 2021
The IMP 2.15.0 release contains minor updates, most notably improved handling of MRC files, a new scoring function for cryo-EM data, and support for Apple Silicon.
Dec 02, 2020
The IMP 2.14.0 release contains minor updates, most notably an overhaul of the IMP::kinematics and IMP::parallel modules, and support for Python 3.9.
May 14, 2020
The IMP 2.13.0 release contains major updates, most notably support for Ubuntu 20.04, Focal Fossa, and a new IMP::sampcon module to estimate the highest precision at which the sampling is exhaustive.
Dec 06, 2019
The IMP 2.12.0 release contains major updates, most notably support for Python 3.8 and RHEL/CentOS 8, and a new IMP::bayesianem module for Bayesian handling of cryo-electron microscopy density map data.
Jul 18, 2019
The IMP 2.11.1 release contains bug fixes, most notably fixing some issues with the build system, failures to read RMF files, and cloning of molecular hierarchies.
Jun 25, 2019
The IMP 2.11.0 release contains bug fixes and major updates, most notably updates to the build system and a new set of tutorials.
Feb 26, 2019
The IMP 2.10.1 release contains minor bug fixes.
Jan 08, 2019
The IMP 2.10.0 release contains bug fixes and major updates, most notably an overhaul of the IMP::pmi module.
Jul 02, 2018
The IMP 2.9.0 release contains bug fixes and major updates, including elucidation of the structure of the entire yeast nuclear pore complex.
Aug 16, 2017
The IMP 2.8.0 release contains bug fixes and minor updates, including two new applications of IMP, and the Anaconda and Windows pre-built binary packages are now MPI-enabled. This release also includes a number of bug fixes and performance improvements. Note that this will be the last release that includes packages for Ubuntu 12.04 (Precise Pangolin) since it has reached end of life.
Apr 13, 2017
The IMP 2.7.0 release contains bug fixes and major updates, including a preview of mmCIF support for deposition of integrative models in PDB-Dev. See the IMP::pmi::mmcif module for more details. This release also includes a number of bug fixes and performance improvements. Note that this will be the last release that includes packages for RedHat Enterprise Linux 5 (and variants, such as CentOS 5), since RHEL 5 has reached end of life.
May 25, 2016
The IMP 2.6.2 release contains minor bug and documentation fixes, including support for Ubuntu 16.04 (Xenial Xerus).
Apr 14, 2016
The IMP 2.6.1 release contains minor bug and documentation fixes.
Mar 28, 2016
The IMP 2.6.0 release contains bug fixes and minor updates. Most notably we include most of the functionality of PMI2. This is an improved version of PMI that is faster than PMI1, more modular, and easier to use. See IMP::pmi for more information. This release also includes a number of bug fixes, most notably in the creation of sampled electron microscopy density maps.
Jun 30, 2015
The IMP 2.5.0 release contains bug fixes and minor updates. Most notably the documentation has been revised and updated; we now provide binary packages for Ubuntu 12.04 (Precise Pangolin) in addition to 14.04 (Trusty Tahr); a lot of obsolete and deprecated functionality has been removed; support for OpenMP and MPI is improved; and the IMP::base and IMP::kernel namespaces are now deprecated in favor of the top-level "IMP" namespace.
Feb 27, 2015
The IMP 2.4.0 release contains bug fixes and updates. Most notably Python 3 is now supported, and a new tutorial example that determines the structure of part of RNA Polymerase II, using the IMP::pmi module, is now available.
Dec 01, 2014
The IMP 2.3.1 release is a bug fix and minor update release. Most notably two complete modeling examples that use the IMP::pmi module are now fully functional: modeling of the Nup84 subcomplex of the nuclear pore complex and of RNA Polymerase II.
Oct 24, 2014
The IMP 2.3.0 release contains bug fixes and updates. Most notably the experimental IMP::pmi module is now available. This provides a variety of high-level Python classes to simplify the construction of a modeling protocol in IMP. One recent use of PMI is the modeling of the Nup84 subcomplex of the nuclear pore complex. We also now provide binary packages for Ubuntu LTS and 64-bit Windows.
Aug 11, 2014
The IMP 2.2.1 release contains minor updates to 2.2.0, including build and documentation fixes and a fix for the ligand_score application.
Apr 9, 2014
The IMP 2.2.0 release contains a number of new features, notably support for SOAP scoring and a more reliable RMF file format.
Nov 4, 2013
The IMP 2.1.1 release contains minor updates to 2.1.0, most notably support for the new Mac OS X release (Mavericks).
Oct 24, 2013
The IMP 2.1.0 release contains bug fixes and updates. We now provide several fully worked examples of biological systems that were investigated with IMP, from our own publications.
May 02, 2013
The IMP 2.0.1 release contains several new applications to tackle certain modeling problems, including
  • EMageFit to build assembly models using electron microscopy images (class averages)
  • multifit and cnmultifit to build assembly models using electron microscopy density maps
  • Integrative docking to improve pairwise docking using a variety of additional experimental information sources
  • saxs_merge, a fully automated statistical method for merging small-angle X-ray (SAXS) profiles using Gaussian processes
Dec 2011
IMP has been employed to translate tethered conformation capture (TCC) data into physical chromatin contacts in a population of three-dimensional genome structures. Statistical analysis of the resulting population demonstrates that the indiscriminate properties of interchromosomal interactions are consistent with the well-known architectural features of the human genome. more...
Jan 2011
IMP has been used by researchers at the Centro de Investigación Príncipe Felipe in Spain, in combination with chromosome conformation capture carbon copy (5C) technology, to generate high-resolution three-dimensional models of chromatin at the megabase scale. [publication 1]   [publication 2]
2007
Researchers from UCSF and the Rockefeller University have used IMP for modeling the Nuclear Pore Complex. more...