IMP  2.0.1
The Integrative Modeling Platform

A protocol for generating atomic structures of complexes with cyclic symmetry (such as rings), using only the atomic structure of a single subunit and a cryo-electron microscopy density map of the complex. This employs the IMP::cnmultifit module.

See also multifit for a similar protocol operating on non-symmetric complexes.

A webserver is also available.



Author(s): Keren Lasker

Maintainer: benmwebb

License: LGPL This library is free software; you can redistribute it and/or modify it under the terms of the GNU Lesser General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version.


  • Keren Lasker, Maya Topf, Andrej Sali, “Determining macromolecular assembly structures by molecular docking and fitting into an electron density map”, Journal of Molecular Biology, 2009.
  • Keren Lasker, Daniel Russel, Jeremy Phillips, Haim Wolfson, Andrej Sali, “Determining architectures of macromolecular assemblies by aligning interaction networks to electon microscopy density maps”, submitted