IMP  2.0.1
The Integrative Modeling Platform

A method for merging SAXS profiles using Gaussian processes.

Small-Angle X-ray Scattering (SAXS) is an experimental technique that allows gathering structural information on biomolecules in solution. High-quality SAXS profiles are usually obtained by manual merging of scattering profiles from different concentrations and exposure times.

SAXS Merge is a fully automated statistical method for merging SAXS profiles using Gaussian processes. This method requires only the buffer-subtracted profile files in a specific order. At the heart of its formulation is nonlinear interpolation using Gaussian Processes, which provide a statement of the problem that accounts for correlation in the data.

A webserver is also available.


Author(s): Yannick Spill

Maintainer: yannickspill

License: LGPL This library is free software; you can redistribute it and/or modify it under the terms of the GNU Lesser General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version.


  • See main IMP papers list.