This tutorial introduces the functionality in IMP to handle cross-linking data and apply it in modeling.

This tutorial can be followed in several ways:

• Paste the Python code seen in this text into a Python console.
• Download the files from GitHub and, using Jupyter Notebook, open the notebook index.ipynb.
• Load the tutorial directly in your browser, courtesy of Google Colaboratory. (This needs no software installed on your machine, but may take a while to load.)

The following sections introduce different aspects of cross-linking:

• Introduction to cross-linking
• How to deal with ambiguity