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Re: [IMP-users] protein structure generation from sequences with IMP

On 04/10/2012 12:40 PM, Adhikari, Badri (MU-Student) wrote:
We are working on a project in which we need to generate protein models
from the amino acid sequences, using IMP.

If you want to build extended chain structures, see

If you have some extra knowledge (e.g. stereochemistry, atom-atom distances) you can then add that in as restraints and sample.

If you want to build homology models, IMP doesn't do that - you can use our MODELLER package to do that instead.

If you want to build ab initio models, you might want to try a tool like Rosetta.

"It is a capital mistake to theorize before one has data."
	- Sir Arthur Conan Doyle